The continuously updated Coronavirus typing tool of Genome Detective allows the identification of all the WHO SARS-CoV-2 Variants of Concern. Downstream analysis of genomic and transcriptomic sequence data is often executed by functional annotation that can be performed by various bioinformatics tools and biological databases. In addition to the groundbreaking work of professor Tulio de Oliveira in South Africa, many other laboratories throughout the world were enabled in this pandemic to analyze their genomic SARS-CoV-2 data using Genome Detective, by virtue of its ease of use. The MPI Bioinformatics Toolkit for protein sequence analysis Andreas Biegert, Christian Mayer, Michael Remmert, Johannes Soding, and Andrei N. Lalign is considered as one of the most reliable tool for local alignment of nucleotide and amino acid sequences. Basic analysis for a user-entered sequence includes restriction sites and map. Professor Tulio de Oliveira, the director of the Centre for Epidemic Response & Innovation ( CERI) (Stellenbosch, South Africa), started sampling SARS-CoV-2 genomes early in the pandemic for this purpose, and used Genome Detective to discover the Beta and Omicron variants. Here we developed CHOmics, a web-based tool for integrative analysis of CHO cell line omics data that provides an interactive visualization of omics analysis outputs and efficient data management. motif discovery (support genome-wide data sets like ChIP-seq) transcription factor binding motif analysis (quality assessment, comparisons and clustering). Open collection of AAV data generously shared by scientists. It offers data upload/download, sequence-based feature calculation, data.
#WEB BASED TOOLS FOR SEQUENCE ANALYSIS SOFTWARE#
Results: We have developed the web-based software tool SPiCE for exploring sequence-based features of proteins in predefined classes. Genome Detective accurately and quickly assembles viruses to characterize the mutations of the SARS-CoV-2 virus. This lack of easily accessible software hampers quick, explorative use of sequence-based classification techniques by biologists.
From the beginning, Genome Detective has been contributing to SARS-CoV-2 genomic surveillance around the globe with our intuitive bioinformatics platform and genomic database. Geneyx offers a superior NGS data analysis and interpretation platform, Harnessing genetic data to guide digital insights for rare and germline disorders. During the SARS-CoV-2 pandemic, genomic epidemiological surveillance around the world became crucial to guide governmental policies and to monitor the emergence of new variants.
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